CRYSTAL STRUCTURE OF CYTOCHROME P450 3A4 AND ITS USE

CRYSTAL STRUCTURE OF CYTOCHROME P450 3A4 AND ITS USE

The invention provides the crystal structure of the cytochrome P450 3A4 protein molecule. The structure is set out in Table 5. The structure may be used in to model the interaction of compounds such as pharmaceuticals with this protein, and to determine the structure of related cytochrome P450 molec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PAMELA, ANN WILLIAMS, HARREN JHOTI, IAN, JAMES TICKLE, CLEMENS VONRHEIN, STEWART, BRIAN KIRTON
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention provides the crystal structure of the cytochrome P450 3A4 protein molecule. The structure is set out in Table 5. The structure may be used in to model the interaction of compounds such as pharmaceuticals with this protein, and to determine the structure of related cytochrome P450 molecules.