Acyloxypyrrolidine derivatives and use thereof as ligands of V1B or both V1B and V1A receptors

The invention relates to acyloxypyrrolidine derivatives of general formula (I): in which: R1 represents a hydrogen atom, a (C1-C6)alkyl, a (C3-C6)cycloalkyl, a group -CH2CH2COOH or a group -NR2R3; R2 and R3 each represent, independently, a hydrogen atom or a (C1-C6)alkyl. Also disclosed and claimed...

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Bibliographische Detailangaben
Hauptverfasser:	CLAUDINE SERRADEIL-LE GAL, JEAN WAGNON, ALAIN AULOMBARD, GEORGES GARCIA, ANTOINE PRADINES
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to acyloxypyrrolidine derivatives of general formula (I): in which: R1 represents a hydrogen atom, a (C1-C6)alkyl, a (C3-C6)cycloalkyl, a group -CH2CH2COOH or a group -NR2R3; R2 and R3 each represent, independently, a hydrogen atom or a (C1-C6)alkyl. Also disclosed and claimed are the method of preparation of the compounds of the invention and their application in therapeutics.