Cyclohexyl sulphones as gamma-secretase inhibitors

Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.

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Bibliographische Detailangaben
Hauptverfasser:	SUSANNAH WILLIAMS, JOANNE THOMSON, ANDREW PATE OWENS, ALAN JOHN NADIN, DUNCAN EDWARD SHAW, IAN CHURCHER, TIMOTHY HARRISON, SONIA KERRAD
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.