SOLID PREPARATION CONTAINING DIOCTYL SODIUM SULFOSUCCINATE
Dioctyl sodium sulfosuccinate, which is a waxy substance and thus can be hardly processed into a common preparation being coated with an enteric film or the like and thus released around the large intestine, is released at the upper part of the digestive tract and, therefore, is not highly efficacio...
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Zusammenfassung: | Dioctyl sodium sulfosuccinate, which is a waxy substance and thus can be hardly processed into a common preparation being coated with an enteric film or the like and thus released around the large intestine, is released at the upper part of the digestive tract and, therefore, is not highly efficacious from the viewpoint of its direct action. Accordingly, it is intended to provide a solid preparation from which dioctyl sodium sulfosuccinate is released around the large intestine (i.e., the action site) to exert a favorable purgative effect. Namely, a solid preparation characterized in that core particles containing granules, which are obtained by granulating a powder containing light silicic anhydride with the use of a solution containing dioctyl sodium sulfosuccinate, are coated with an enteric film. |
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