Concentrate of a factor VIII:C-containing von Willebrand factor and the process relating thereto

Von Willebrand factor (vWF) concentrates (I) containing Factor VIII:C (FVIII:C) are obtained by fractional precipitation from a liquid containing FVIII:C and vWF; and have an elevated content of high molecular multimers of vWF and a ratio of vWF:RCoF (ristocetin cofactor) activity to vWF:Ag of more...

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Hauptverfasser:	NATASCHA MAYER, STEFAN SCHULTE, GERHARDT KUMPE, WILFRIED WORMSBACHER, MANFRED JURASCHEK
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Von Willebrand factor (vWF) concentrates (I) containing Factor VIII:C (FVIII:C) are obtained by fractional precipitation from a liquid containing FVIII:C and vWF; and have an elevated content of high molecular multimers of vWF and a ratio of vWF:RCoF (ristocetin cofactor) activity to vWF:Ag of more than 1, are new. An Independent claim is included for the preparation of (I).