USE OF DENSIN-LIKE COMPOUNDS

The invention is related to the use of densin-like compounds expressed in glomerular podocytes as well as nucleic acids encoding densin and binding substances specifically recognizing and binding to or interacting with densin-like compounds which are useful for manufacturing products including test...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HARRY HOLTHOFER, HEIKKI AHOLA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention is related to the use of densin-like compounds expressed in glomerular podocytes as well as nucleic acids encoding densin and binding substances specifically recognizing and binding to or interacting with densin-like compounds which are useful for manufacturing products including test kits for diagnosing and treating glomerular diseases manifesting with proteinuria due to hereditary, infectious, inflammatory, toxic or metabolic reasons, IgA nephropathy, membranous, diabetic, crescentic and minimal change nephropathies as well as nephropathy associated with hypertension and infections including HIV associated nephropathy.