Solenopsin a, b and analogs as novel angiogenesis inhibitors

The present invention relates to solenopsin A and its analogs for use as angiogenesis inhibitors. The present compounds unexpectedly exhibit good activity as angiogenesis inhibitors, which find use as antitumor/anticancer agents as well as to treat a number of conditions or disease states in which a...

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Hauptverfasser: PHILLIP J. BOWEN, DAVID WHITMORE, JACK L. ARBISER, SCOTT M. FURNESS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to solenopsin A and its analogs for use as angiogenesis inhibitors. The present compounds unexpectedly exhibit good activity as angiogenesis inhibitors, which find use as antitumor/anticancer agents as well as to treat a number of conditions or disease states in which angiogenesis is a factor.