1,1- AND 1,2-BISPHOSPHONATES AS APOLIPROTEIN E MODULATORS

The present invention relates to methods of use 1,1- and 1,2-bisphosphonate compounds to modulate apolipoprotein E levels and use of such compounds in therapy, including cardiovascular and neurological disease states.

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Bibliographische Detailangaben
Hauptverfasser:	HIEU, TRUNG PHAN, EMANUELE BURATTINI, JEAN-LUC THUILLARD, YVES GUYON-GELLIN, LAN, MONG NGUYEN, ANNE PEREZ, VINH, VAN DIEP, CARLO SEVERI, ERIC, JOSEPH NEISOR, CRAIG, LEIGH BENTZEN, IMBER, FLORES MONTES
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The present invention relates to methods of use 1,1- and 1,2-bisphosphonate compounds to modulate apolipoprotein E levels and use of such compounds in therapy, including cardiovascular and neurological disease states.