SUBSTITUTED PYRIMIDINE-2,4(1H,3H)-DIONES FOR USE AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS

SUBSTITUTED PYRIMIDINE-2,4(1H,3H)-DIONES FOR USE AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS

The invention relates to substituted condensed pyrimidine-2,4(1H,3H)-diones of general formula (I), to their tautomers, stereoisomers, blends, prodrugs and salts, whereby in formula (I) the variables are defined as cited in the description. Said compounds constitute matrix metalloproteinase inhibito...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: UWE KLAUSMEIER, JOCHEN HEINICKE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to substituted condensed pyrimidine-2,4(1H,3H)-diones of general formula (I), to their tautomers, stereoisomers, blends, prodrugs and salts, whereby in formula (I) the variables are defined as cited in the description. Said compounds constitute matrix metalloproteinase inhibitors and are therefore suitable for producing medicaments for treating cancer, rheumatism, inflammation and allergic reactions.