Aerosol formulation for inhalation comprising a tiotropium salt

A medicament preparation (A) comprises: (1) a tiotropium salt as active agent (I) at a tiotropium concentration of 0.01-0.06 g/100 ml, (I) being in completely dissolved form; (2) water as sole solvent; (3) acid to adjust the pH to 2.7-3.1 (preferably 2.8-3.05); (4) a preservative; (5) a complexant a...

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Bibliographische Detailangaben
Hauptverfasser:	BARBARA NIKLAUS-HUMKE, PETRA BARTH, CHRISTEL SCHMELZER, KARIN DRECHSEL
Format:	Patent
Sprache:	eng
Schlagworte:	APPLYING LIQUIDS OR OTHER FLUENT MATERIALS TO SURFACES, IN GENERAL ATOMISING APPARATUS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE NOZZLES PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPRAYING APPARATUS SPRAYING OR ATOMISING IN GENERAL TRANSPORTING
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Beschreibung
Zusammenfassung:	A medicament preparation (A) comprises: (1) a tiotropium salt as active agent (I) at a tiotropium concentration of 0.01-0.06 g/100 ml, (I) being in completely dissolved form; (2) water as sole solvent; (3) acid to adjust the pH to 2.7-3.1 (preferably 2.8-3.05); (4) a preservative; (5) a complexant and/or stabilizer; and optionally (6) other auxiliaries and additives. An independent claim is also included for the production of (A), by mixing the individual components. ACTIVITY : Antiinflammatory; Antiasthmatic; Respiratory-Gen.. MECHANISM OF ACTION : Anticholinergic.