N-(3-RIFAMYCINYL)-CARBAMATES, METHOD OF PREPARING THEM AND THEIR USE FOR TREATING AND PREVENTING TUBERCULOSIS

The present invention relates to novel N-(3-rifamycinyl)-derivatives, namely N-(3-rifamycinyl)-carbamates, methods of their preparation and their use for the production of pharmaceutical preparations. The invention also concerns a composition and a method for treating or preventing mycobacterial inf...

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Hauptverfasser: GERRIT SCHUURMANN, ZOYA, ANDONOVA NEDEYALKOVA, OVANES MEKENYAN, JASON, ANTHONY SHARPE, ASENOV GROZDANOV, RALPH KUHNE, PETER, WILLIAM ANDREW, DESISLAVA, TODOROVA MINCHEVA, STEVKA, TZVETKOVA PARASKEVOVA, NELY, TZONEVA ANGELOVA, SASHKO, IVANOV DEKIN, SVETLANA, TZVETKOVA HALADGOVA, PAVEL, NENOV PENEV, JAMILIA SHAFI, ISKRA, TODOROVA ATANASOVA, DIMCHO, IVANOV DIMOV
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel N-(3-rifamycinyl)-derivatives, namely N-(3-rifamycinyl)-carbamates, methods of their preparation and their use for the production of pharmaceutical preparations. The invention also concerns a composition and a method for treating or preventing mycobacterial infections, especially tuberculosis. Formula (I);