Amino nicotinate derivatives as glucokinase (GLK) modulators

The invention is related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relat...

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Bibliographische Detailangaben
Hauptverfasser:	DARREN MCKERRECHER, ROGER JAMES, RODNEY BRIAN HARGREAVES, PETER WILLIAM RODNEY CAULKETT, CRAIG JOHNSTONE, GORDON STUART CURRIE, JOANNE VICTORIA ALLEN, BARRY RAYMOND HAYTER, CLIFFORD DAVID JONES, HAROLD GASKIN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention is related to novel compounds of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, useful in the treatment of a disease or condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to methods for preparing compounds of Formula (I) and their use as medicaments in the treatment of diseases mediated by glucokinase.