Method of producing 1-hydroxy-1,1-diphosphonic acid compounds

In a method for preparing 1-hydroxy-1,1-diphosphonic acid compounds of the general formula I and/or of their pharmacologically compatible salts a compound of the formula II is reacted with a compound P(OSiR53)3-pR6p and the reaction product is hydrolyzed.

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Bibliographische Detailangaben
Hauptverfasser: HELMUT BLUM, GERD-VOLKER ROSCHENTHALER, YURII PUSTOVIT, WOLFGANG GREB
Format: Patent
Sprache:eng
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Zusammenfassung:In a method for preparing 1-hydroxy-1,1-diphosphonic acid compounds of the general formula I and/or of their pharmacologically compatible salts a compound of the formula II is reacted with a compound P(OSiR53)3-pR6p and the reaction product is hydrolyzed.