Endogenous and non-endogenous versions of human G protein-coupled receptors

Endogenous and non-endogenous versions of human G protein-coupled receptors

The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown, and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.

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Bibliographische Detailangaben
Hauptverfasser: RUOPING CHEN, CAMERON PRIDE, ZHI LIANG CHU
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor for which the endogenous ligand is unknown, and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.