Method for introducing nucleic acids and other biologically active molecules into the nucleus of higher eukaryotic cells by means of an electrical current

Introducing a biologically active molecule (I) into the nucleus of eukaryotic cells, comprising applying an electrical pulse of field strength 2-10 kV/cm; duration at least 10 Micros and current at least 1 Amp, is new. - ACTIVITY : None given. - MECHANISM OF ACTION : Gene therapy. No biological data...

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Hauptverfasser:	CORINNA THIEL, LUDGER ALTROGGE, KIRSTEN ROTHMANN, RAINER CHRISTINE, MARION GREMSE, GREGOR SIEBENKOTTEN, GUDULA RIEMEN, DIETMAR LENZ, SABINE POPPENBORG
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Introducing a biologically active molecule (I) into the nucleus of eukaryotic cells, comprising applying an electrical pulse of field strength 2-10 kV/cm; duration at least 10 Micros and current at least 1 Amp, is new. - ACTIVITY : None given. - MECHANISM OF ACTION : Gene therapy. No biological data is given.