Amidino compounds useful as nitric oxide synthase inhibitors

Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.

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Bibliographische Detailangaben
Hauptverfasser: SOFYA TSYMBALOV, RICHARD C. DURLEY, RICHARD R. SCHARTMAN, TIMOTHY J HAGEN, DONALD W. HANSEN, FOE SIONG TJOENG, BARNETT S PITZELE, PAMELA T. MANNING, BRIAN S. HICKORY, ALOK K. AWASTHI, GOPICHAND YALAMANCHILI, W. GARY PHILLIPS, MICHELLE A. PROMO, ARIJA A BERGMANIS, MAHIMA TRIVEDI, MICHAEL MAO, KAM F FOK, JEFFREY S. SNYDER, RICHARD VONDER EMBSE, RONALD KEITH WEBBER, MIHALY V TOTH, SCOTT S. GANSER, JEFFREY A. SCHOLTEN, ALAN E MOORMANN, ANN E. HALLINAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33: where the substituents are described herein.