Use of IL-18 inhibitors

The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheu...

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Bibliographische Detailangaben
Hauptverfasser: CHARLES DINARELLO, SANTER VAN DEVENTER, YOLANDE CHVATCHKO, DANIELA NOVICK, SOO-HYUN KIM, CHRISTINE PLATER-ZYBERK, MENA RUBINSTEIN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheumatoid arthritis. In addition to this, the invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of inflammatory bowel diseases, in particular of Crohn's disease and ulcerative colitis.