PEPTIDE BORONIC ACID INHIBITORS OF TRYPSIN-LIKE PROTEASES
Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, of the formula are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin.
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Zusammenfassung: | Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, of the formula are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin. |
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