NOVEL DERIVATIVES OF GUANINE I

Novel antiviral compounds of the formula wherein R1 is hydrogen, R2 is hydrogen, fluoro, methoxy or methylthio and R3 is hydrogen, hydroxy or mercapto; with the provisos that when R3 is hydrogen then R2 is methoxy or methylthio and that when R3 is hydroxy then R2 is fluoro, methoxy or methylthio; an...

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Hauptverfasser: GOTTHAMMAR, KRISTINA BIRGITTA, EKLIND, KARIN INGEBORG, STENING, GORAN BERTIL, HAGBERG, CURT-ERIK, JOHANSSON, KARL NILS-GUNNAR, KOVACS, ZSUZSANNA MARIA ILONA, NOREN, JAN-OLOF
Format: Patent
Sprache:eng
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Zusammenfassung:Novel antiviral compounds of the formula wherein R1 is hydrogen, R2 is hydrogen, fluoro, methoxy or methylthio and R3 is hydrogen, hydroxy or mercapto; with the provisos that when R3 is hydrogen then R2 is methoxy or methylthio and that when R3 is hydroxy then R2 is fluoro, methoxy or methylthio; and with the further proviso that R1 can also be methoxy or fluoro when R2 is methoxy or fluoro; and physiologically acceptable salts or optical isomers thereof, methods for their preparation, pharmaceutical compositions containing the compounds, and use of said compounds in the treatment of virus infections.