QUINOXALINE PHOSPHONO-AMINO ACIDS

QUINOXALINE PHOSPHONO-AMINO ACIDS

The compounds of the formula: in which Q is the quinoxaline nucleus; m is one of the integers 0, 1 or 2; n is one of the integers 1,2 or 3; or a pharmaceutically acceptable salt, alkyl ester or where R3 and R4 are, independently, hydrogen, nitro, halo or methoxy, are NMDA antagonists useful in the t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: REINHARDT BERNHARD BAUDY, LYNNE PADILLA GREENBLATT, IVO LADISLAV JIRKOVSKY
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The compounds of the formula: in which Q is the quinoxaline nucleus; m is one of the integers 0, 1 or 2; n is one of the integers 1,2 or 3; or a pharmaceutically acceptable salt, alkyl ester or where R3 and R4 are, independently, hydrogen, nitro, halo or methoxy, are NMDA antagonists useful in the treatment and prevention of central nervous system related pathological conditions resulting from overstimulation by excitatory amino acids.