Compositions and methods for systemic delivery of oral vaccines and therapeutic agents

Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.

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Bibliographische Detailangaben
Hauptverfasser: NIKITA KIYATKIN, ANDREW MAKSYMOWYCH, LANCE SIMPSON
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.