PYRAZIN-DERIVATE ALS ARNEIMITTEL ZUR KONTROLLE UND/ODER SENKUNG DES SERUM TRIGLYZERIDUND/ODER- CHOLESTEROLSPIEGELS IN SAEUGETIEREN

The use of at least one compound of Formula (I) for the manufacture of a medicament for controlling and/or reducing a patient's serum cholesterol and/or triglyceride level is disclosed. wherein Y is O or NH, R is OH, NHCONR R ; or N=C(NR R )2;where R and R are each independently selected from the group consisting of hydrogen; C1-10alkyl, straight or branched chain; aryl C1-4alkyl; mono- or disubstituted aryl C1-4 alkyl where the substituents are fluoro, chlore, bromo, iodo, or C1-10alkyl, straight or branched chain; R and R are each independently selected from the group consisting of hydrogen, animo, and mono- or di-substituted amino where the substituents are C1-10alkyl, straight or branched chain, C3-8 cycloalkyl; provided that R and R may not both be amino or substituted amino and; R is hydrogen, trifluoromethyl, fluoro; chloro, bromo, or iodo, or a pharmaceutically acceptable salt thereof. e