VERFAHREN ZUR HERSTELLUNG VON ANTIKOERPERZUSAMMENSETZUNGEN VON THERAPEUTISCHEN MITTELN MIT VERLAENGERTER SERUMHALBWERTZEIT

A therapeutic agent e.g. alpha-interferon, complexes with an antibody without impairing the activity. The antibody can be a monoclonal antibody. The serum half-life of the therapeutic agent administered as the complex is substantially increased when compared to that of the agent administered alone.

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Bibliographische Detailangaben
Hauptverfasser: FRINCKE, JAMES M, GUTTERMAN, JORDAN UDELL, BURNETT, KAREN G, ROSENBLUM, MICHAEL GORDON, UNGER, BARBARA W, HERSH, EVAN MYRON
Format: Patent
Sprache:eng ; ger
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Beschreibung
Zusammenfassung:A therapeutic agent e.g. alpha-interferon, complexes with an antibody without impairing the activity. The antibody can be a monoclonal antibody. The serum half-life of the therapeutic agent administered as the complex is substantially increased when compared to that of the agent administered alone.