KONDENSIERTE BICYCLISCHE CARBONSÄUREAMIDDERIVATE ZUR VERWENDUNG ALS CXCR2-INHIBITOREN BEI DER BEHANDLUNG VON ENTZÜNDUNGEN

KONDENSIERTE BICYCLISCHE CARBONSÄUREAMIDDERIVATE ZUR VERWENDUNG ALS CXCR2-INHIBITOREN BEI DER BEHANDLUNG VON ENTZÜNDUNGEN

The invention relates to compounds of the formula I in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and the pharmaceutically acceptable salts thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds o...

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Hauptverfasser: GRUENEBERG, SVEN, SHIMSHOCK, STEPHEN, LI, HUI, WEICHSEL, ALEKSANDRA, LANTER, CAROLINA, CZECHTIZKY, WERNGARD, HACHTEL, STEPHANIE, HEITSCH, HOLGER, DEDIO, JUERGEN, SHER, ROSY, KOSLEY, RAYMOND
Format: Patent
Sprache:ger
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Zusammenfassung:The invention relates to compounds of the formula I in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and the pharmaceutically acceptable salts thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts thereof are suitable for the prevention and treatment of chemokine mediated diseases such as inflammation.