ÄÄ3-(2-AMINO-1,2-DIOXOETHYL)-2-ETHYL-1- (PHENYLMETHYL)-11H-INDOL-4-YLÜOXYÜESSIGSÄURE METHYL ESTER ALS SPLA2 INHIBITOR

ÄÄ3-(2-AMINO-1,2-DIOXOETHYL)-2-ETHYL-1- (PHENYLMETHYL)-11H-INDOL-4-YLÜOXYÜESSIGSÄURE METHYL ESTER ALS SPLA2 INHIBITOR

A class of novel 1H-indole-3-glyoxylamides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

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Bibliographische Detailangaben
Hauptverfasser: DILLARD, ROBERT DELANE, BACH, NICHOLAS JAMES, DRAHEIM, SUSAN ELIZABETH
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A class of novel 1H-indole-3-glyoxylamides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.