SPALTUNG VON VEGF UND VEGF-REZEPTOREN DURCH WILDTYP- UND MUTANTE MT-SP1

SPALTUNG VON VEGF UND VEGF-REZEPTOREN DURCH WILDTYP- UND MUTANTE MT-SP1

MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis.

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Bibliographische Detailangaben
Hauptverfasser: RUGGLES, SANDRA, NGUYEN, JACK
Format: Patent
Sprache:ger
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Zusammenfassung:MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis.