CHIMERES, VON DEN PLACENTA- UND HYPOPHYSENISOFORMEN ABGELEITETES HUMANES WACHSTUMSHORMON UND VERFAHREN ZUR GEWINNUNG DER CHIMERE

A way to increase the production of recombinant polypeptides by combining pieces of several different isoforms of a given gene to make a chimeric isoform of the gene (using a chimeric gene can increase the production of polypeptide over 25%), or by inserting several copies of the coding region in ta...

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Hauptverfasser: BORBHUIYA, AHMED MONSUR, RAO, SRINIVAS, MISHRA, SHRIKANT, NIPHADKAR, PRABHAKAR, KHARE, GANESH ARUNA, MAITI, DIPANWITA
Format: Patent
Sprache:ger
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Zusammenfassung:A way to increase the production of recombinant polypeptides by combining pieces of several different isoforms of a given gene to make a chimeric isoform of the gene (using a chimeric gene can increase the production of polypeptide over 25%), or by inserting several copies of the coding region in tandem into a transformation vector (e.g., plasmids carrying multiple copies of the chimera of SEQ ID NO: 3 increased production 107%).