VERFAHREN ZUR UMWANDLUNG VON INTERFERON-ISOFORMEN UND DARAUS HERGESTELLTE PRODUKTE

VERFAHREN ZUR UMWANDLUNG VON INTERFERON-ISOFORMEN UND DARAUS HERGESTELLTE PRODUKTE

The present invention provides methods for isolating adjunct isoforms of proteins and converting them to the desired protein. In preferred embodiments, the present invention contemplates the use of acid solutions or zinc solutions to cleave a chemical group from a desired protein. In further preferr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MENGISEN, ROLAND, VOLOCH, MARCIO, WYLIE, DAVID, FREI, ANDRES, LEE, SEOJU, CANNON-CARLSON, SUSAN
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides methods for isolating adjunct isoforms of proteins and converting them to the desired protein. In preferred embodiments, the present invention contemplates the use of acid solutions or zinc solutions to cleave a chemical group from a desired protein. In further preferred embodiments, the present invention contemplates the oxidation of reduced sulfhydryl groups with cleavage of chemical groups to form a functional desired protein.