TRIAZOLOPYRIDAZINE ALS PROTEINKINASE-INHIBITOREN

The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of PIM-1, CDK-2, GSK-3, and SRC mammalian protein kinases. The invention also provides pharmaceutically acceptable compo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GREEN, JEREMY, PIERCE, ALBERT, GREY, RONALD JR
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of PIM-1, CDK-2, GSK-3, and SRC mammalian protein kinases. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.