N-SUBSTITUIERTE 2-AMINOTHIAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE THERAPEUTISCHE ANWENDUNG
The subject of the invention is N-substituted 2-aminothiazoles of formula (I) in which: X is a C-H group or a nitrogen atom, R1 and R2 are, independently of each other, a hydrogen atom, a halogen atom or an alkyl, alkoxy, alkylthio, alkenyloxy, cycloalkyl, trifluoromethyl, nitro, amino, (C1-C6 alkyl...
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| creator | BONNE, CLAUDE COQUELET, CLAUDE SINCHOLLE, DANIEL 343 AVENUE DE LA TRE RIVIERE ALAZET, ALAIN |
| description | The subject of the invention is N-substituted 2-aminothiazoles of formula (I) in which: X is a C-H group or a nitrogen atom, R1 and R2 are, independently of each other, a hydrogen atom, a halogen atom or an alkyl, alkoxy, alkylthio, alkenyloxy, cycloalkyl, trifluoromethyl, nitro, amino, (C1-C6 alkyl)amino or di(C1-C6 alkyl)-amino radical, and R3 is a hydrogen atom, a -CH2-OH group or a -COOR4 group, R4 being a hydrogen atom or an alkyl group, and also the pharmaceutically acceptable salts thereof. These compounds have an anti-inflammatory and antiallergic activity and can be used in therapy, especially in the ocular field. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | N-SUBSTITUIERTE 2-AMINOTHIAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE THERAPEUTISCHE ANWENDUNG |
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