N-SUBSTITUIERTE 2-AMINOTHIAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE THERAPEUTISCHE ANWENDUNG

N-SUBSTITUIERTE 2-AMINOTHIAZOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE THERAPEUTISCHE ANWENDUNG

The subject of the invention is N-substituted 2-aminothiazoles of formula (I) in which: X is a C-H group or a nitrogen atom, R1 and R2 are, independently of each other, a hydrogen atom, a halogen atom or an alkyl, alkoxy, alkylthio, alkenyloxy, cycloalkyl, trifluoromethyl, nitro, amino, (C1-C6 alkyl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BONNE, CLAUDE, COQUELET, CLAUDE, SINCHOLLE, DANIEL 343 AVENUE DE LA TRE, RIVIERE, ALAZET, ALAIN
Format: Patent
Sprache:fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The subject of the invention is N-substituted 2-aminothiazoles of formula (I) in which: X is a C-H group or a nitrogen atom, R1 and R2 are, independently of each other, a hydrogen atom, a halogen atom or an alkyl, alkoxy, alkylthio, alkenyloxy, cycloalkyl, trifluoromethyl, nitro, amino, (C1-C6 alkyl)amino or di(C1-C6 alkyl)-amino radical, and R3 is a hydrogen atom, a -CH2-OH group or a -COOR4 group, R4 being a hydrogen atom or an alkyl group, and also the pharmaceutically acceptable salts thereof. These compounds have an anti-inflammatory and antiallergic activity and can be used in therapy, especially in the ocular field.