2-Ä-3--2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL - CYCLOHEXYLMETHOXYÜ-PROPIONSÄURE DERIVATE ALS PPAR-LIGANDEN (PEROXISOMEN-PROLIFERATOREN-AKTIVIERTE REZEPTOREN) ZUR BEHANDLUNG VON HYPERLIPIDÄMIE UND DIABETES

2-Ä-3--2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL - CYCLOHEXYLMETHOXYÜ-PROPIONSÄURE DERIVATE ALS PPAR-LIGANDEN (PEROXISOMEN-PROLIFERATOREN-AKTIVIERTE REZEPTOREN) ZUR BEHANDLUNG VON HYPERLIPIDÄMIE UND DIABETES

The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistance and the like comprising acetic acid derivatives with cyclohexylmethox...

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Bibliographische Detailangaben
Hauptverfasser: KNIEPS, STEPHANIE, WENDLER, WOLFGANG, STAPPER, CHRISTIAN, FALK, EUGEN, SCHAEFER, HANS-LUDWIG, KEIL, STEFANIE, GLOMBIK, HEINER
Format: Patent
Sprache:ger
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Zusammenfassung:The present invention comprises compounds and compositions for the treatment of metabolic disorders and more particularly, those insulin-related metabolic disorders of the blood such as hyperlipidemia, diabetes, insulin-resistance and the like comprising acetic acid derivatives with cyclohexylmethoxy substituents and their salts. Known as peroxisome proliferator-activated receptors (PPAR) agonists/antagonists, the invention relates to compounds of the formula I wherein the various substituent R-groups are more specifically defined herein.