SELEKTIONSVERFAHREN FÜR EINE DURCH DAS AUSTESTEN EINER PPARD AKTIVIERENDEN WIRKUNG CHARAKTERISIERTEN SUBSTANZ UND ARZNEISTOFF

Selection (M1) of substances which accelerate thermogenesis, accelerate the uncoupling of respiration in mitochondria, accelerate protein leak in mitochondrial internal membranes, increase the expression level of UCP1 in cells containing mitochondria, and/or accelerate fatty acid beta-oxidation, com...

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Bibliographische Detailangaben
Hauptverfasser:	CHIKANISHI, TOSHIHIRO, KATAOKA, KENICHIRO, YAMAMOTO, MASANORI, YAMAOKA, KAZUYOSHI, TAKAGI, KENICHIRO
Format:	Patent
Sprache:	ger
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Selection (M1) of substances which accelerate thermogenesis, accelerate the uncoupling of respiration in mitochondria, accelerate protein leak in mitochondrial internal membranes, increase the expression level of UCP1 in cells containing mitochondria, and/or accelerate fatty acid beta-oxidation, comprising selection for activation of peroxisome proliferator activated receptor delta (PPARD), is new. An independent claim is also included for drug compositions containing substances identified by (M1). ACTIVITY : Antidiabetic; Anorectic. MECHANISM OF ACTION : Activation of PPARD. No biological data given.