VERFAHREN ZUR WAERMEBEHANDLUNG EINER DEN MENSCHLICHEN BLUTGERINNUNGSFAKTOR VIII ENTHALTENDEN WAESSRIGEN LOESUNG

Human blood coagulation factor VIII which may have hepatitis virus activity can be virus-inactivated with keeping at a minimum the damage of the factor VIII by heating its aqueous solution at 50 to 80°C for 3 to 15 hours in the presence of 10% (WN) or more of at least one principal stabilizer of neu...

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Hauptverfasser:	SUYAMA, TADAKAZU, IGA, YOSHIRO, NAITO, RYOICHI
Format:	Patent
Sprache:	eng ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Human blood coagulation factor VIII which may have hepatitis virus activity can be virus-inactivated with keeping at a minimum the damage of the factor VIII by heating its aqueous solution at 50 to 80°C for 3 to 15 hours in the presence of 10% (WN) or more of at least one principal stabilizer of neutral amino acids, monosaccharides, oligosaccharides, and sugar alcohols and 10% (WN) or more of at least one auxiliary stabilizer of salts of hydrocarbon and hydroxyhydrocarbon carboxylic acids having 3 to 10 carbon atoms.