VERFAHREN ZUR CHARAKTERISIERUNG DER GLYCOSILIERUNG VON SIALOGLYCOPROTEINEN ÜBER EINE ISOFORMENZAHL I
A method is described for characterization of the quality of a sialoglycoprotein via its isoform number I which is calculated from the isoform distribution of the capillary electrophoretic analysis of the sialoglycoprotein and represents a quality feature for the batch consistency, storage stability...
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Sprache: | ger |
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Zusammenfassung: | A method is described for characterization of the quality of a sialoglycoprotein via its isoform number I which is calculated from the isoform distribution of the capillary electrophoretic analysis of the sialoglycoprotein and represents a quality feature for the batch consistency, storage stability, biological half-life and the biological effectiveness of a therapeutic glycoprotein. Uses of this method are also described. |
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