1,5-DIPHENYLPYRAZOLIN-3-ON-VERBINDUNGEN SOWIE VERFAHREN UND ZWISCHENPRODUKTE ZU IHRER HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL

Intermediates of the isomeric formulae II or III II III wherein R1 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxyl, trifluoromethyl or lower alkanoyloxy group, R2 is a hydrogen or halogen atom, or a lower alkyl or lower alkoxy group, or R1 and R2 are bonded to adjacent carbon...

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Hauptverfasser: JASSERAND, DANIEL, MILKOWSKI, WOLFGANG...RE, YAVORDIOS, DIMITRI, HEINEMANN, HENNING...RER, ZEUGNER, HORST.. ER.NAT
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Sprache:ger
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Zusammenfassung:Intermediates of the isomeric formulae II or III II III wherein R1 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxyl, trifluoromethyl or lower alkanoyloxy group, R2 is a hydrogen or halogen atom, or a lower alkyl or lower alkoxy group, or R1 and R2 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethylenedioxy group, R3 is a hydrogen or halogen atom, or a lower alkyl, lower alkoxy, hydroxy, trifluoromethyl or lower alkanoyloxy group, R4 is a hydrogen or halogen atom, or a lower alkyl or lower alkoxy group, or R3 and R4 are bonded to adjacent carbon atoms and together denote a methylenedioxy or ethylenedioxy group, Z is an alkylene group with 2 to 6 carbon atoms, Z' is an alkylene group with 2 to 4 carbon atoms, Y is a halogen atom, and Y' is a halogen atom, and acid addition salts thereof, are useful to prepare antiallergic 2-piperazinoalkyl-1, 5-diphenylpyrazolin-3-ones.