4-AMINO-5-OXO-8-PHENYL-5H-PYRIDO-Ä2,3-DÜ- PYRIMIDIN-DERIVATE ALS INHIBITOREN DER TYROSINKINASEN UND DER RAF-KINASEN ZUR BEHANDLUNG VON TUMOREN

4-AMINO-5-OXO-8-PHENYL-5H-PYRIDO-Ä2,3-DÜ- PYRIMIDIN-DERIVATE ALS INHIBITOREN DER TYROSINKINASEN UND DER RAF-KINASEN ZUR BEHANDLUNG VON TUMOREN

Compounds of the formula (I), in which R6, R7, R8, R9, Het1, X and X′ have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.

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Bibliographische Detailangaben
Hauptverfasser: RAUTENBERG, WILFRIED, JONCZYK, ALFRED, ROSELL-VIVES, ELISABET, ACKERMANN, KARL-AUGUST, ADAN, JAUME, HOELZEMANN, GUENTER, CASES, CLAUDIA, TARRASON, GEMA, CRASSIER, HELENE
Format: Patent
Sprache:ger
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Zusammenfassung:Compounds of the formula (I), in which R6, R7, R8, R9, Het1, X and X′ have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours.