VERWENDUNG EINER EPIDERMALEN WACHSTUMSFAKTOR (EGF) ENTHALTENDEN PHARMAZEUTISCHEN ZUSAMMENSETZUNG ZUR VERMEIDUNG EINER FUSSAMPUTATION BEI DIABETES

Use of epidermal growth factor (EGF) in a composition for treating a lesion, ischemic or caused by reperfusion, in a diabetic patient, by local infiltration into the tissues that form the borders and base of the lesion, is new. An independent claim is also included for a pharmaceutical composition (...

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Hauptverfasser:	HERRERA MARTINEZ, LUIS, GUILLEN NIETO, GERARDO E, CANAN-HADEN FRIAS, LEONARDO, FRANCO PEREZ, NEOBALIS, VALDES PEREZ, CALIXTO, CHACON CORVEA, LARISSA, FERNANDEZ MONTEQUIN, JOSE I, GERONIMO PEREZ, HAYDEE, BERLANGA ACOSTA, JORGE, SOTOLONGO PENA, JORGE, ROJAS CONSTANTIN, INGRID, SANTANA MILIAN, HECTOR
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Use of epidermal growth factor (EGF) in a composition for treating a lesion, ischemic or caused by reperfusion, in a diabetic patient, by local infiltration into the tissues that form the borders and base of the lesion, is new. An independent claim is also included for a pharmaceutical composition (liquid or freeze-dried) for treating the specified lesions that contains 10-1000 Microg/ml of EGF combined with at least one of fibronectin; raffinose; poly(ethyleneimine); an isoflavonoid (e.g. rutin); lidocaine; adenosine or guanosine triphosphates, or their salts; nicotinamide; L-Arg or heparin salt. ACTIVITY : Antidiabetic; Vulnerary. MECHANISM OF ACTION : Stimulation of cell proliferation.