BETULINSÄUREDERIVATE ZUR INHIBIERUNG DES KREBSWACHSTUMS UND EIN VERFAHREN ZU IHRER HERSTELLUNG

BETULINSÄUREDERIVATE ZUR INHIBIERUNG DES KREBSWACHSTUMS UND EIN VERFAHREN ZU IHRER HERSTELLUNG

The invention relates to novel betulinic acid derivatives of structural formula having modifications at C2, C3, C17, C20 and/or C29 positions, said derivatives being useful as inhibitors of tumor/cancer cells; process for preparation of the said derivatives; pharmaceutical compositions comprising sa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JAGGI, MANNU, RAMADOSS, SUNDER, SIDDIQUI, MOHAMMAD, KHANNA, ACHLA
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Beschreibung
Zusammenfassung:The invention relates to novel betulinic acid derivatives of structural formula having modifications at C2, C3, C17, C20 and/or C29 positions, said derivatives being useful as inhibitors of tumor/cancer cells; process for preparation of the said derivatives; pharmaceutical compositions comprising said derivatives useful in the treatment of ovarian, colon, lung, laryngeal, prostrate cancer, leukemia, lymphoma and a method of treatment of ovarian, colon, lung, laryngeal and prostrate cancer in mammals using said derivatives or compositions.