RACEMISCHE UND OPTISCH AKTIVE 7-OXO-PROSTACYCLIN- DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE PHARMAZEUTISCHE PRAEPARATE

RACEMISCHE UND OPTISCH AKTIVE 7-OXO-PROSTACYCLIN- DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE PHARMAZEUTISCHE PRAEPARATE

Compounds of the formula I are disclosed wherein R1 stands for hydrogen, C1-4 straight or branched alkyl or pharmacologically acceptable cation, R2 stands for hydrogen, C1-4 alkanoyl, benzoyl, or benzoyl substituted by C1-4 alkyl or halogen, and R2 can further represent tetrahydropyranyl, trialkylsi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GALAMBOS, GEZA, KANAY, KAROLY, TOEMOESKOEZI, ISTVAN, DORMAN, GYOERGY, VIRAG, SANDOR, IVANICS, JOZSEF, GYOERY, PETER, STADLER, ISTVAN, KOERMOECZY, PETER, KOVACS, GABOR, KOVACS, MARIANNA
Format: Patent
Sprache:ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Compounds of the formula I are disclosed wherein R1 stands for hydrogen, C1-4 straight or branched alkyl or pharmacologically acceptable cation, R2 stands for hydrogen, C1-4 alkanoyl, benzoyl, or benzoyl substituted by C1-4 alkyl or halogen, and R2 can further represent tetrahydropyranyl, trialkylsilyl or alkoxyalkyl, A stands for ethylene, cis or trans-vinylene or -C=C-, n may represent 2, 3 or 4. The compounds are highly effective in the inhibition of thrombocyte aggregation while at the same time exert only a very small hypotensive effect.