VORRICHTUNGEN ZUR VERABREICHUNG VON ARZNEISTOFFEN MIT ANTIPROGESTINISCHEN EIGENSCHAFTEN

A device for the controlled release over a prolonged period of time of a drug having antiprogestinic properties, the device including a core containing the drug, optionally a membrane encasing the core, where at least one of the core and membrane, when present, is made of a siloxane-based elastomer...

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Bibliographische Detailangaben
Hauptverfasser: JUKARAINEN, HARRI, MARKKULA, TOMMI, LEHTINEN, MATTI, ALA-SORVARI, JUHA, RUOHONEN, JARKKO, HAAPAKUMPU, TIMO
Format: Patent
Sprache:ger
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Zusammenfassung:A device for the controlled release over a prolonged period of time of a drug having antiprogestinic properties, the device including a core containing the drug, optionally a membrane encasing the core, where at least one of the core and membrane, when present, is made of a siloxane-based elastomer composition including at least one elastomer and optionally a non-crosslinked polymer. The device is characterized in that the elastomer composition includes poly(alkylene oxide) groups and that the poly(alkylene oxide) groups are present in the elastomer or polymer as alkoxy-terminated grafts of polysiloxane units, or as blocks, the grafts or blocks being linked to the polysiloxane units by silicon-carbon bonds, or as a mixture of these forms.