VERFAHREN ZUR HERSTELLUNG VON 6-ALPHA-FLUORO,9,11-BETA-EPOXY-STEROIDE
Described herein is a process for the preparation of 6 alpha -fluorosteroids of formula (I), in which R is chosen from H, OH and an alkyl group with from 1 to 4 carbon atoms and R' is a carboxyalkyl group with from 1 to 4 carbon atoms in the alkyl chain, comprising the selective fluorination at...
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| Zusammenfassung: | Described herein is a process for the preparation of 6 alpha -fluorosteroids of formula (I), in which R is chosen from H, OH and an alkyl group with from 1 to 4 carbon atoms and R' is a carboxyalkyl group with from 1 to 4 carbon atoms in the alkyl chain, comprising the selective fluorination at the 6 alpha -position by treatment of the compound of formula (III), wherein R and R' are as defined above, with an electrophilic fluorinating agent. |
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