PROTEASERESISTENTE FLINT-ANALOGE

The invention relates to FLINT analogs that are resistant to proteolysis in vivo and in vitro at amino acid position 218 of mature FLINT, clinical and therapeutic uses thereof, and pharmaceutical formulations comprising said analogs.

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Bibliographische Detailangaben
Hauptverfasser: MICANOVIC, RADMILA, RATHNACHALAM, RADHAKRISHNAN, WITCHER, DERRICK
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:The invention relates to FLINT analogs that are resistant to proteolysis in vivo and in vitro at amino acid position 218 of mature FLINT, clinical and therapeutic uses thereof, and pharmaceutical formulations comprising said analogs.