ZYKLISCHE SOMATOSTATIN-ANALOGE MIT EINER HAUPTKETTE MIT EINER GESPANNTEN KONFORMATION

Novel peptide analogs are disclosed. The novel peptides are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comp...

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Hauptverfasser: SERI-LEVY, ALON, HORNIK, VERED, GILON, CHAIM, GELLERMAN, GARY
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creator SERI-LEVY, ALON
HORNIK, VERED
GILON, CHAIM
GELLERMAN, GARY
description Novel peptide analogs are disclosed. The novel peptides are conformationally constrained backbone cyclized somatostatin analogs. Methods for synthesizing the somatostatin analogs and for producing libraries of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions in the treatment of endocrine disorders, neoplasms and metabolic disorders are also disclosed.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEASURING
MEASURING ELECTRIC VARIABLES
MEASURING MAGNETIC VARIABLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
title ZYKLISCHE SOMATOSTATIN-ANALOGE MIT EINER HAUPTKETTE MIT EINER GESPANNTEN KONFORMATION
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