DERIVATE VON 3-PHENYL-N-(2-(4-BENZYL)PIPERIDIN-1- YL)ETHYL) ACRYLAMID MIT CCR-3-REZEPTOR ANTAGONISTISCHER WIRKUNG ZUR VERWENDUNG BEI DER BEHANDLUNG VON ENTZÜNDUNGEN UND ALLERGISCHEN LEIDEN

This invention relates to organic compounds of formula I, in which Ar1 is unsubstituted phenyl substituted by one or more halogen atoms; Ar2 is unsubstituted phenyl or phenyl substituted by one or more substituents selected from the group consisting of halogen, cyano and C1-C8-alkoxy; R1 is hydrogen...

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Hauptverfasser: WALKER, CLIVE VICTOR, BHALAY, GURDIP
Format: Patent
Sprache:ger
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Zusammenfassung:This invention relates to organic compounds of formula I, in which Ar1 is unsubstituted phenyl substituted by one or more halogen atoms; Ar2 is unsubstituted phenyl or phenyl substituted by one or more substituents selected from the group consisting of halogen, cyano and C1-C8-alkoxy; R1 is hydrogen or methyl optionally substituted by hydroxy; R10 is hydrogen or hydroxy; and pharmaceutically acceptable salts thereof. Compositions containing them, methods for their preparation and their use as pharmaceuticals are also described.