VERBESSERUNGEN DER SPEZIFITÄT DER GENEXPRESSION

This invention seeks to improve the specificity of gene expression by targeting a specific expression site of a target gene. There is thus provided a chimaeric gene which comprises a promoter which expresses in more than one region of the organism to be affected. The promoter is linked to an agent w...

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Bibliographische Detailangaben
Hauptverfasser: THOMAS, CHRISTOPHER, JOHN, ROBERT, O'REILLY, DAVID
Format: Patent
Sprache:ger
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Beschreibung
Zusammenfassung:This invention seeks to improve the specificity of gene expression by targeting a specific expression site of a target gene. There is thus provided a chimaeric gene which comprises a promoter which expresses in more than one region of the organism to be affected. The promoter is linked to an agent which affects the functioning of an endogenous gene in the plant which is also expressed in more than one region of the plant. The promoter and agent are selected so that there is an overlap in their expression sites at one or more desired locations. This overlap site(s) gives increased specificity and targeting of gene expression.