SYNTHESE VON 9-DEOXO-9A-AZA 11,12-DEOXY-9A-METHYL-9A-HOMOERYTHROMYCIN A 11,12-HYDROGENORTHOBORAT- DIHYDRAT

SYNTHESE VON 9-DEOXO-9A-AZA 11,12-DEOXY-9A-METHYL-9A-HOMOERYTHROMYCIN A 11,12-HYDROGENORTHOBORAT- DIHYDRAT

The preparation of azitromicin dihydrate from 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12-hydrogenorthoborate, obtained by a step by step process starting from 9-deoxo-6-deoxy-6,9-epoxy-9,9a-dihydro-9a-azahomoerythromycin A is a process which takes place under mild conditions an...

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Bibliographische Detailangaben
Hauptverfasser: BAYOD JASANADA, MIGUEL SANTOS, FERNANDEZ GONZALEZ, JOSE RAMON
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Zusammenfassung:The preparation of azitromicin dihydrate from 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12-hydrogenorthoborate, obtained by a step by step process starting from 9-deoxo-6-deoxy-6,9-epoxy-9,9a-dihydro-9a-azahomoerythromycin A is a process which takes place under mild conditions and with good yields.