THALIDOMIDANALOGE VERBINDUNGEN AUS DER KLASSE DER PIPERIDIN-2,6-DIONE

THALIDOMIDANALOGE VERBINDUNGEN AUS DER KLASSE DER PIPERIDIN-2,6-DIONE

Piperidin-2,6-dione derivatives of formula (I) are new. Z = (a) -C(R1)(R2)CH2- or (b) -C(R1)=CH-; R1 = phthalimide when Z = (a) or phthalimide mono- or disubstituted by OH, CH3O or NH2 when Z = (b); R2 = H or 1-6C alkyl; R3 = H, 1-6C alkyl or heteroaromatic ring; and R4 = 1-6C alkyl or (hetero)aroma...

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Bibliographische Detailangaben
Hauptverfasser: WINTER, WERNER, DR, TEUBERT, UWE, ZIMMER, OSWALD, EGER, KURT, DR, WNENDT, STEPHAN, ZWINGENBERGER, KAI
Format: Patent
Sprache:ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Piperidin-2,6-dione derivatives of formula (I) are new. Z = (a) -C(R1)(R2)CH2- or (b) -C(R1)=CH-; R1 = phthalimide when Z = (a) or phthalimide mono- or disubstituted by OH, CH3O or NH2 when Z = (b); R2 = H or 1-6C alkyl; R3 = H, 1-6C alkyl or heteroaromatic ring; and R4 = 1-6C alkyl or (hetero)aromatic ring.