SUBSTITUIERTE POLYZYKLISCHE ARYL UND HETEROARYLPYRAZINONE ZUR SELEKTIVEN HEMMUNG VON DER BLUTGERINNUNGSKASKADE

The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions includ...

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Hauptverfasser:	FENTON, RICK, WOOD, RHONDA, LONG, SCOTT, A, LINDMARK, RICHARD, HAYES, MICHAEL, J, TRUJILLO, JOHN, I, DICE, TOM, MAHONEY, MATTHEW, W, CASE, BRENDA, REITZ, DAVID B, PARLOW, JOHN, J, WANG, CHINGNG, ZENG, QINGPING, SOUTH, MICHAEL, S, HUANG, WEI, HUANG, HORNGIH, NEUMANN, WILLIAM, L, JONES, DARIN, E, FRANKLIN, GARY, W, RUEPPEL, MELVIN, L, KUSTURIN, CARRIE
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.