NICHT-PEPTIDISCHE GNRH AGENTIA, VERFAHREN UND ZWISCHENVERBINDUNGEN ZUR IHREN HERSTELLUNG

Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent t...

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Bibliographische Detailangaben
Hauptverfasser:	TOMPKINS, EILEEN, VALENZUELA, PADERES, GENEVIEVE, DEGUZMAN, HONG, YUFENG, CHRISTIE, LANCE, CHRISTOPHER, PATHAK, VED, P, VAZIR, HARESH, N, FAUST, JAMES, LUTHIN, DAVID, ROBERT, LI, HAITAO, ANDERSON, MARK, BRIAN
Format:	Patent
Sprache:	ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.